The Mangekyou Sharingan is an evolved form of Sharingan in Naruto. It is said that a Sharingan user awakens their Mangekyou Sharingan when they are subjected to immense emotional trauma, which is usually triggered by the tragic death of a loved one. This evolved eye technique grants them unimaginable powers, usually two distinct abilities, one in each eye.
When someone awakens Mangekyou Sharingan in both of their eyes, they are blessed with the ability to summon a Susano’o, one of the strongest powers in Naruto. So, on that note, here are some of the strongest Mangekyou Sharingan and their users who have distinguished themselves from others in Naruto.
1. Sasuke Uchiha
Sasuke is among the strongest Uchiha of all time in the Naruto series. He awakened his Mangekyou Sharingan after the demise of his brother Itachi. His eyes granted him the power of Amaterasu and complete manipulation of flame. Impressively, the great Fourth Raikage even lost an arm to Sasuke’s deadly black flames.
He also gained the power to use a full-body Susano’o, making him an extremely formidable opponent. Over time, Sasuke’s left eye evolved into a Rinnegan, granting him the ultimate power in the process.
2. Indra Otsutsuki
Hagoromo’s eldest son was Indra Otsutsuki, who inherited the visual technique from his father. He awakened his Mangekyou Sharingan and trained it to the extent that he was called the strongest Sharingan user. Moreover, he possessed the ability to summon a full Susano’o with just the Mangekyou Sharingan. Although his prowess wasn’t shown much within the series, but since he had a great reputation, it is believed he was one of the strongest beings in Naruto to ever live.
3. Madara Uchiha
Madara Uchiha, along with his brother Izuna, was the first person to awaken the powers of the Mangekyou Sharingan. He made his Sharingan possess the ultimate power by transplanting his brother’s eyes into his, making the Eternal Mangekyou Sharingan.
Madara’s Mangekyou Sharingan allowed him the prowess to summon a full-body Susano’o, which was strong enough to slice through mountain ranges with a simple slash. He stole several other Mangekyou Sharingan and mastered their innate abilities as well. Moreover, his expertise with the technique was seen when he stole Kakashi’s eye and easily used the Kamui.
4. Obito Uchiha
Obito Uchiha is known to be one of the strongest Uchiha to ever exist. His Mangekyou Sharingan was awakened during the Third Great Ninja War after witnessing his teammate Rin die. He possessed the power of Kamui, a powerful space-time ninjutsu. With just one Sharingan, Obito was strong enough that people confused him with the Ghost of the Uchiha, i.e., Madara.
Moreover, he put up a fight against the fourth Hokage, Minato Namikaze, who was also his former mentor, at a very young age. He used his Sharingan to manipulate the Nine Tails and launched a devastating attack on the Hidden Leaf Village. Following this, he honed his skills over the years and acquired insane control over his only eye.
5. Itachi Uchiha
Itachi Uchiha is one of the best Mangekyou Sharingan users in the series. After the death of his best friend, Shisui, he awakened his Mangekyou Sharingan. He indulged in immense training to hone the powers of the Tsukuyomi and the Amaterasu.
An intelligent shinobi, his ability to use the technique was unmatched. Itachi also used Shisui’s Mangekyou Sharingan to release himself from Kabuto’s Edo Tensei during the Fourth Shinobi War. He was able to utilize the powers of the Susano’o to an impressive extent. His version even wielded the Totsuka Blade and the Yata Mirror, making him almost invincible in combat.